The global unveiling follows last month's world premiere of the LS 500 with its twin-turbo 3.5-litre V6 petrol engine.
Designed to exceed expectations, the next-generation LS is destined to redefine and advance definitions of luxury motoring and customer satisfaction - just as the first LS did when it launched Lexus onto the global stage 28 years ago.
The 2018 LS - due in Australia early next year - features a strikingly bold design with a coupe-like silhouette that rides on a new platform delivering unprecedented agility and comfort.
At Geneva, Lexus will also debut a redesigned motor-show stand that showcases the brand's hallmark craftsmanship, quality and safety while giving visitors an immersive experience.
The Lexus press conference will take place on 7 March at 12:45pm (10.45pm AEDT) on stand no. 4211 in Hall 4, Palexpo.